An advanced course presenting aspects and applications of pharmacokinetics, pharmacodynamics and kinetic/dynamic data analysis in the medical and pharmaceutical sciences.
For whom intended:
The Course is designed for those who have a good working knowledge of basic concepts in pharmacokinetics, pharmacodynamics and data analysis and who now wish to extend their knowledge further. Emphasis will be placed on relating pharmacokinetics to underlying physiological processes and to pharmacodynamics, and on the analysis and modelling of pharmacokinetic and pharmacodynamic data.
Course content:
The mornings will be devoted to lectures; the late afternoons to small-group workshops led by experienced tutors, in which participants will solve practical problems and develop facility with the techniques and approaches discussed in the lectures. The participants are encouraged to raise questions from their experience for discussion: time is specifically reserved for informal consultations.
Course manual:
A course manual, comprising lecture outlines, derivations, problem sets with answers, and additional reading material will be provided in an electronic format.
This is not a computer modelling training course. There are no computer exercises. However, participants should come with a scientific hand calculator or notebook computer.
Ability to understand and converse in English is essential.
Registration and Local Details:
Registration places are limited. Early booking is recommended. The Workshop is limited to 60 applicants only. Ability to understand and converse in English is essential. A limited number of places, at a reduced fee, are available to academic persons. Further details are available upon request to [email protected]
PAYMENT
Once you have successfully registered on the course, you will receive the bank transfer details in order to pay for your workshop attendance.
TIMETABLE
The 2026 Workshop starts at 1800 hrs Sunday 22nd March 2026 and finishes at 1230 hrs Friday 27th March 2026.
LOCATION OF WORKSHOP
Hotel Waldhaus (5 star), Sils-Maria, Engadin Valley, Switzerland. A picturesque and tranquil setting close to St. Moritz. The hotel has an indoor swimming pool, sauna and indoor tennis court.
ACCOMMODATION AND MEALS
Accommodation will be available through the nights of course duration at Hotel Waldhaus. Each room has a private bathroom. The costs of accommodation and all meals are included in the Workshop.
FREE TIME
The early afternoons are free for personal pursuits.
PUBLIC TRANSPORTATION
The Engadin Valley is readily reached by car. For those coming by air or rail there are regular trains to Sils-Maria from Zurich via Chur. Exact details and timetables can be found at www.rail.ch.
CAR PARKING
A car park is available within the grounds of Hotel Waldhaus.
TIMETABLE (Preliminary Version – subject to change)
Sunday 22nd March
18:00 Welcome and pick-up manual
19.00 Dinner
Monday 23rd March
08:45-09:00 Introduction (Leon Aarons)
09:00-10:15 Lecture 1 – Empirical Pharmacokinetics (Leon Aarons)
10:15-10:45 Coffee
10:45-12:00 Lecture 2 – Pharmacodynamic Principles (Lena Friberg)
12:30-14:00 Lunch
15:00-16:00 Consultation (optional)
16:00-19:00 Workshop I – Empirical PK and PD Principles
19:00 Reception
19:30 Dinner
Tuesday 24th March
09:00-10:15 Lecture 3 – Physiologically Based Pharmacokinetics (Leon Aarons)
10:15-10:45 Coffee
10:45-12:00 Lecture 4 – PKPD Principles (Nick Holford)
12:30-14:00 Lunch
15:00-16:00 Consultation (optional)
16:00-19:00 Workshop II – PBPK and PKPD Principles
19:30 Dinner
Wednesday 25th March
09:00-10:15 Lecture 5 – Nonlinear regression (Leon Aarons)
10:15-10:45 Coffee
10:45-12:00 Lecture 6 – Population PKPD – Models & methods (Mats Karlsson)
12:30-14:00 Lunch
15:00-16:00 Consultation (optional)
16:00-19:00 Workshop III – Nonlinear regression and Population PK
19:30 Dinner
Thursday 26th March
09:00-10:15 Lecture 7 – Population PKPD – Modelling (Mats Karlsson)
10:15-10:45 Coffee
10:45-12:00 Lecture 8 – Disease Progression Principles (Nick Holford)
12:30-14:00 Lunch
15:00-16:00 Consultation (optional)
16:00-19:00 Workshop IV – Population PKPD and Disease Progression Principles
19:30 Course Dinner
Friday 27th March
09:00-10:15 Lecture 9 – To be Announced
10:15-10:45 Coffee
10:45-12:00 Lecture 10 – Concentration Guided Dosing (Nick Holford)
12:00 Lunch
END OF COURSE