Sunday April 8 through Friday April 13
An advanced course presenting aspects and applications of pharmacokinetics, pharmacodynamics and kinetic/dynamic data analysis in the medical and pharmaceutical sciences.
For whom intended:
The Course is designed for those who have a good working knowledge of basic concepts in pharmacokinetics, pharmacodynamics and data analysis and who now wish to extend their knowledge further. Emphasis will be placed on relating pharmacokinetics to underlying physiological processes and to pharmacodynamics, and on the analysis and modelling of pharmacokinetic and pharmacodynamic data.
Course content:
The mornings will be devoted to lectures; the late afternoons to small-group workshops led by experienced tutors, in which participants will solve practical problems and develop facility with the techniques and approaches discussed in the lectures. The participants are encouraged to raise questions from their experience for discussion: time is specifically reserved for informal consultations.
Course manual:
A course manual, comprising lecture outlines, derivations, problem sets with answers, and additional reading material will be provided in an electronic format.
This is not a computer modelling training course. There are no computer exercises. However, participants should come with a scientific hand calculator or notebook computer.
Ability to understand and converse in English is essential.
Registration and Local Details:
http://www.pkworkshops.com/adv-wksp2018.htm
TIMETABLE (Preliminary Version – subject to change)
Sunday 8th April
18:00 Welcome and pick-up manual
19.00 Dinner
Monday 9th April
08:45-09:00 Introduction (Leon Aarons)
09:00-10:15 Lecture 1 – Empirical Pharmacokinetics (Leon Aarons)
10:15-10:45 Coffee
10:45-12:00 Lecture 2 – Pharmacodynamic Principles (Steve Duffull)
12:30-14:00 Lunch
15:00-16:00 Consultation (optional)
16:00-19:00 Workshop I – Empirical PK/PD Principles
19:00 Reception
19:30 Dinner
Tuesday 10th April
09:00-10:15 Lecture 3 – Physiologically Based Pharmacokinetics (Leon Aarons)
10:15-10:45 Coffee
10:45-12:00 Lecture 4 – PKPD Principles (Nick Holford)
12:30-14:00 Lunch
15:00-16:00 Consultation (optional)
16:00-19:00 Workshop II – PBPK/PKPD Principles
19:30 Dinner
Wednesday 11th April
09:00-10:15 Lecture 5 – Nonlinear regression (Leon Aarons)
10:15-10:45 Coffee
10:45-12:00 Lecture 6 – Population PKPD – Models & methods (Mats Karlsson)
12:30-14:00 Lunch
15:00-16:00 Consultation (optional)
16:00-19:00 Workshop III – Nonlinear regression/Population PK
19:30 Dinner
Thursday 12th April
09:00-10:15 Lecture 7 – Population PKPD – Modelling (Mats Karlsson)
10:15-10:45 Coffee
10:45-12:00 Lecture 8 – Disease Progression Principles (Nick Holford)
12:30-14:00 Lunch
15:00-16:00 Consultation (optional)
16:00-19:00 Workshop IV – Population PKPD/Disease Progression Principles
19:30 Course Dinner
Friday `13th April
09:00-10:15 Lecture 9 – Optimal design (Steve Duffull)
10:15-10:45 Coffee
10:45-12:00 Lecture 10 – Models for discrete data (Steve Duffull)
12:00 Lunch
END OF COURSE